CJH332H Summer 2023 Final Assessment
Test Format
- Multiple Choice and True/False Questions (20 Questions, 20 Marks in total)
- Short Answer Questions (5 Questions, 20 Marks in total)
Material Covered
- Basics of optogenetics
- Stereotaxic surgery
- Channelrhodopsin
- Viral vectors
- Calcium imaging
- Calcium indicator
- Genetic encoded calcium indicator (GECI)
- Fiber photometry
- Neurotransmitter sensors
- Fear memory and lateral amygdala
- Diphtheria toxin mechanism
- Inducible Diphtheria Toxin Receptor (iDTR)
- Designer receptor exclusively activated by a designer drug (DREADD)
- Chemogenetics
- Excitatory and inhibitory DREADDs
- Long-term potentiation (LTP)
- Long-term depression (LTD)
- Spike-timing dependent plasticity
- Synaptic plasticity
- AMPAR and NMDAR in LTP
- Risk factors of stroke
- Transient ischemic attacks (TIA)
- Types of stroke
- Neuroanatomy of stroke
- Olney’s glutamate excitotoxicity
- Animal models of stroke
- Repairs in stroke
- Synucleinopathies
- Parkinson’s disease (PD)
- Dopamine neurons in substantia nigra
- Animal models of PD
- α-synuclein pathology
- Lewy bodies
- Multiple system atrophy (MSA)
- Symptoms of MSA
- Rapid eye movement (REM) sleep behaviour disorder (RBD)
- Braak’s hypothesis
Test Content
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