CJH332H Winter 2022 Term Test 3

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Test Format

  • Multiple Choice and True/False Questions (20 Questions, 20 Marks in total)
  • Short Answer Questions (5 Questions, 20 Marks in total)

Material Covered

  • Basics of optogenetics
  • Stereotaxic surgery
  • Channelrhodopsin
  • Cre-lox system
  • Viral vectors
  • Dale’s principle
  • Calcium imaging
  • Calcium indicator
  • Genetic encoded calcium indicator (GECI)
  • Fiber photometry
  • Endoscopic microscope
  • 2-Photons
  • Microdialysis
  • Neurotransmitter sensors
  • Fear memory and lateral amygdala
  • Diphtheria toxin mechanism
  • Inducible Diphtheria Toxin Receptor (iDTR)
  • Designer receptor exclusively activated by a designer drug (DREADD)
  • Chemogenetics
  • Excitatory and inhibitory DREADDs
  • Long-term potentiation (LTP)
  • Long-term depression (LTD)
  • Spike-timing dependent plasticity
  • Synaptic plasticity
  • AMPAR and NMDAR in LTP

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